Polyester is already found in two out of three items of clothing. But while the global demand for synthetic fibres continues to rise, their production consumes valuable resources. Can living organisms help us to initiate fibre-to-fibre recycling strategies and develop sustainable material cycles? The Break-up Lab researches the potential of the enzymatic degradation of polyester fibres in used textiles and develops recyclable garments. The Break-up Lab is also creating a transparent infrastructure for the collection of used textiles.